Across TCGA patient cohorts, PPP1R14C protein abundance is significantly associated with the RNA expression of many other genes, with 13,504 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPP1R14C-associated genes across cancer lineages are ULBP3, ULBP2, and TMPRSS13. Each is linked with PPP1R14C in more than 6 cancer types. Because this analysis shows association rather than direction, both PPP1R14C-to-partner and partner-to-PPP1R14C results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R14C→partner) and Y-score (partner→PPP1R14C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ULBP3 →	+1.167	+1.654	<.001	<.001	3	7
BRCA	ULBP2 →	+1.255	+1.475	<.001	<.001	3	5
COAD	TMPRSS13 →	+1.693	+0.562	<.001	<.001	3	4
GBM	NECTIN1 →	+0.877	+0.526	<.001	.001	3	4
LSCC	PERP →	+1.117	+1.071	<.001	<.001	3	4
UCEC	MEF2D →	-0.551	-0.880	.002	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,504 associations by consensus.

Exploration

PPP1R14C survival (RNA) · tumor vs normal (RNA) · all PPP1R14C data types