Across TCGA patient cohorts, PPP1R14C mutation is significantly associated with the RNA expression of many other genes, with 135 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R14C-associated genes across cancer lineages are RN7SL384P, MIR3131, and TAF9. Each is linked with PPP1R14C in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R14C-to-partner and partner-to-PPP1R14C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R14C→partner) and Y-score (partner→PPP1R14C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL384P →	+0.122	+4.328	<.001	.007	3	2
SKCM	MIR3131 →	+0.538	+3.979	<.001	.003	3	2
UCEC	TAF9 →	+0.645	+3.343	<.001	.005	3	1
UCEC	STMN1P1 →	+0.398	+3.108	.002	.001	3	1
UCEC	MIR6509 →	+0.430	+2.277	.002	.002	3	1
UCEC	TMEM86A →	-0.538	-2.785	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 135 associations by consensus.

Exploration

PPP1R14C survival (RNA) · tumor vs normal (RNA) · all PPP1R14C data types