protein phosphatase 1 regulatory inhibitor subunit 14B pseudogene 5Genealiases: []
Q-omics provides the consensus-scored PPP1R14BP5 profile across patient tissues and cancer cell-line models. PPP1R14BP5 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, PPP1R14BP5 is differentially expressed in 9, with the highest sampling consensus in HNSC. Additionally, PPP1R14BP5 RNA expression shows 7,300 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight UCEC, HNSC, and GBM as cancer lineages where PPP1R14BP5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PPP1R14BP5 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PPP1R14BP5 survival associations across molecular data types. PPP1R14BP5 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PPP1R14BP5 RNA expression–survival associations across cancer types. High PPP1R14BP5 expression shows unfavorable associations in UCEC, STAD and ACC, but favorable associations in THCA, SKCM and KIRP. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify UCEC as the clearest survival context for PPP1R14BP5 RNA expression.
This table summarizes PPP1R14BP5 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for PPP1R14BP5. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PPP1R14BP5 shows lower tumor expression in THCA and higher tumor expression in HNSC, STAD, LUAD, CHOL and LIHC. The HNSC box plot shows higher PPP1R14BP5 RNA expression in tumor versus normal tissue (log2 FC = +0.118, t-test p < 0.001).
This table shows molecular features associated with PPP1R14BP5 in patient tissues and cancer cell lines. In patient samples, PPP1R14BP5 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
