protein phosphatase 1 regulatory inhibitor subunit 14B pseudogene 2Genealiases: []
Q-omics provides the consensus-scored PPP1R14BP2 profile across patient tissues and cancer cell-line models. PPP1R14BP2 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in PAAD. Among the 18 cancer types available for tumor–normal comparison, PPP1R14BP2 is differentially expressed in 13, with the highest sampling consensus in COAD. Additionally, PPP1R14BP2 RNA expression shows 14,002 significant gene co-expression associations, with the highest sampling consensus in READ. Together, these results highlight PAAD, COAD, and READ as cancer lineages where PPP1R14BP2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PPP1R14BP2 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PPP1R14BP2 survival associations across molecular data types. PPP1R14BP2 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PPP1R14BP2 RNA expression–survival associations across cancer types. High PPP1R14BP2 expression shows unfavorable associations in PAAD, LIHC, CESC, KICH and KIRC, but favorable associations in SKCM. The PAAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .004). Together, the overview and detailed table identify PAAD as the clearest survival context for PPP1R14BP2 RNA expression.
This table summarizes PPP1R14BP2 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for PPP1R14BP2. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PPP1R14BP2 shows higher tumor expression in COAD, HNSC, LUAD, LIHC, STAD and BLCA. The COAD box plot shows higher PPP1R14BP2 RNA expression in tumor versus normal tissue (log2 FC = +1.552, t-test p < 0.001).
This table shows molecular features associated with PPP1R14BP2 in patient tissues and cancer cell lines. In patient samples, PPP1R14BP2 shows the broadest associations at the RNA and protein expression levels, with READ recurring as the lineage with the largest associated feature set.
