PPP1R14A

Across TCGA patient cohorts, PPP1R14A protein abundance is significantly associated with the RNA expression of many other genes, with 9,135 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PPP1R14A-associated genes across cancer lineages are AOC3, HSPB7, and MYH11. Each is linked with PPP1R14A in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP1R14A-to-partner and partner-to-PPP1R14A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R14A versus AOC3 in BRCA, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R14A→partner) and Y-score (partner→PPP1R14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AOC3 →	+0.932	+0.552	.004	.001	3	8
COAD	HSPB7 →	+1.339	+0.792	<.001	<.001	3	8
COAD	MYH11 →	+1.899	+0.754	<.001	<.001	3	8
LUAD	SHE →	+0.806	+0.342	.001	<.001	3	8
LUAD	SGCA →	+0.864	+0.423	<.001	<.001	3	7
GBM	LDB3 →	+1.025	+0.999	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,135 associations by consensus.

PPP1R14A vs AOC3 — BRCA

Explore this scatter interactively →