PPP1R14A

Across TCGA cell cohorts, PPP1R14A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,450 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP1R14A-associated GO terms across cancer lineages are Translational initiation, Protein folding, and Positive regulation of telomere maintenance via telomere lengthening. Each is linked with PPP1R14A in more than 10 cancer types. Because this analysis shows association rather than direction, both PPP1R14A-to-partner and partner-to-PPP1R14A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Translational initiation grouped by PPP1R14A-low versus PPP1R14A-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R14A→partner) and Y-score (partner→PPP1R14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Translational initiation →	+0.075	+1.967	.003	.009	3	11
UPPER_AERODIGESTIVE_TRACT	Protein folding →	+0.046	+0.921	.003	.001	3	10
STOMACH	Positive regulation of telomere maintenance via telomere lengthening →	+0.088	+2.132	.003	.005	2	10
STOMACH	Establishment of protein localization to organelle →	+0.044	+1.518	.003	.006	3	9
OESOPHAGUS	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.112	+2.161	.004	.007	3	9
CNS	Ribosome biogenesis →	+0.061	+1.002	<.001	.009	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,450 associations by consensus.

Translational initiation by PPP1R14A expression — STOMACH

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