PPP1R13L

Across TCGA pan-cancer cohorts, PPP1R13L mass-spec protein differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of PPP1R13L’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PPP1R13L mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types PPP1R13L is over-expressed in tumor, although a few such as HNSC show the opposite, repressed pattern.

COAD, CCRCC, and PDAC are the cancer types where PPP1R13L tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PPP1R13L mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	All	+0.637	<.001	12	view →
CCRCC	Male	IV	+1.007	<.001	11	view →
PDAC	Male	All	+0.414	<.001	9	view →
LSCC	Female	All	+0.561	<.001	8	view →
LUAD	Male	All	+0.223	<.001	6	view →
HNSC	Male	IV	−0.321	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

PPP1R13L–COAD

Open the COAD breakdown →