PPP1R12B

Across TCGA patient cohorts, PPP1R12B protein abundance is significantly associated with the RNA expression of many other genes, with 19,321 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP1R12B-associated genes across cancer lineages are CASQ2, GPIHBP1, and SRPX. Each is linked with PPP1R12B in more than 9 cancer types. Because this analysis shows association rather than direction, both PPP1R12B-to-partner and partner-to-PPP1R12B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R12B versus CASQ2 in HNSC, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R12B→partner) and Y-score (partner→PPP1R12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CASQ2 →	+2.003	+0.680	<.001	<.001	3	10
OV	GPIHBP1 →	+1.148	+0.683	<.001	<.001	3	10
BRCA	SRPX →	+1.199	+0.582	<.001	<.001	3	9
BRCA	CPED1 →	+1.115	+0.555	<.001	<.001	3	9
GBM	ASPA →	+1.205	+0.284	<.001	<.001	3	9
HNSC	SGCA →	+1.189	+0.689	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,321 associations by consensus.

PPP1R12B vs CASQ2 — HNSC

Explore this scatter interactively →