PPP1R11P1

Across TCGA pan-cancer cohorts, PPP1R11P1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated PPP1R11P1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher PPP1R11P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPP1R11P1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

UVM, KIRC, and HNSC are the cancer types where PPP1R11P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	II,III,IV	0.475	0.779	<.001	78	view →
KIRC	DFS	Tertile	IV	0.783	0.546	.005	77	view →
HNSC	DFS	Tertile	All	0.820	0.629	<.001	72	view →
KICH	OS	Tertile	All	0.468	0.958	.001	33	view →
BLCA	DFS	Quartile	IV	0.323	0.518	.011	24	view →
CESC	DFS	Tertile	All	0.902	0.787	.005	24	view →
TGCT	DFS	Quartile	All	0.971	0.735	.003	18	view →
OV	OS	Tertile	IV	0.518	0.279	.018	16	view →
LUAD	DFS	Tertile	IV	0.429	0.912	.002	14	view →
LUSC	OS	Quartile	II,III,IV	0.553	0.335	.011	12	view →
MESO	OS	Tertile	III,IV	0.804	0.538	.043	12	view →
CHOL	OS	Tertile	II,III,IV	0.155	0.706	.015	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

PPP1R11P1–UVM (DFS)

Open the UVM breakdown →