Across TCGA patient cohorts, PPP1R11 protein abundance is significantly associated with the RNA expression of many other genes, with 7,590 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP1R11-associated genes across cancer lineages are SLC9A3R1, PRPF4, and FAM160A1. Each is linked with PPP1R11 in more than 3 cancer types. Because this analysis shows association rather than direction, both PPP1R11-to-partner and partner-to-PPP1R11 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R11→partner) and Y-score (partner→PPP1R11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SLC9A3R1 →	-0.985	-0.201	<.001	<.001	3	3
LSCC	PRPF4 →	-0.680	-0.154	<.001	<.001	3	3
UCEC	FAM160A1 →	-0.678	-0.357	<.001	<.001	3	3
LSCC	STRBP →	-0.779	-0.198	<.001	<.001	3	3
UCEC	TLCD3A →	-0.667	-0.276	<.001	<.001	3	3
LSCC	SAPCD2 →	-1.030	-0.192	.001	.001	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,590 associations by consensus.

Exploration

PPP1R11 survival (RNA) · tumor vs normal (RNA) · all PPP1R11 data types