Across TCGA patient cohorts, PPP1R11 mutation is significantly associated with the RNA expression of many other genes, with 219 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R11-associated genes across cancer lineages are RNU6-336P, DLAT, and SPAG17. Each is linked with PPP1R11 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R11-to-partner and partner-to-PPP1R11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R11→partner) and Y-score (partner→PPP1R11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-336P →	+0.356	+4.594	<.001	.008	3	2
UCEC	DLAT →	+0.890	+3.459	<.001	.005	3	1
UCEC	SPAG17 →	-0.911	-3.459	.006	.005	3	1
UCEC	SLC15A2 →	-1.312	-3.459	<.001	.005	3	1
UCEC	TKT →	+0.724	+3.459	.004	.005	3	1
UCEC	GHITM →	+0.793	+3.459	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 219 associations by consensus.

Exploration

PPP1R11 survival (RNA) · tumor vs normal (RNA) · all PPP1R11 data types