Across TCGA patient cohorts, PPP1R11 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R11-associated genes across cancer lineages are Notch1, p62 Lck ligand, and Annexin-1. Each is linked with PPP1R11 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R11-to-partner and partner-to-PPP1R11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R11→partner) and Y-score (partner→PPP1R11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.241	+3.169	.001	.020	3	1
UCEC	p62 Lck ligand →	+0.641	+3.009	<.001	.019	3	1
UCEC	Annexin-1 →	+0.786	+2.827	.006	.035	3	1
UCEC	Stathmin →	+0.178	+3.169	.018	.020	3	1
UCEC	4E-BP1 →	+0.327	+3.029	.027	.018	3	1
UCEC	eIF4G →	+0.390	+3.169	.022	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

PPP1R11 survival (RNA) · tumor vs normal (RNA) · all PPP1R11 data types