PPP1R11

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PPP1R11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,204 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PPP1R11-associated GO terms across cancer lineages are Nuclear membrane organization, Regulation of interleukin-6-mediated signaling pathway, and Endoplasmic reticulum to cytosol transport. Each is linked with PPP1R11 in more than 8 cancer types. Because this analysis shows association rather than direction, both PPP1R11-to-partner and partner-to-PPP1R11 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R11→partner) and Y-score (partner→PPP1R11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUENuclear membrane organization →+0.068+0.591<.001<.00139
LUNG_NSCLC_LUSCRegulation of interleukin-6-mediated signaling pathway →+0.180+1.138.008.00439
SOFT_TISSUEEndoplasmic reticulum to cytosol transport →+0.112+0.680.001<.00138
SOFT_TISSUEBrush border assembly →-0.758-0.505.002.00138
SOFT_TISSUERetrograde protein transport, ER to cytosol →+0.112+0.680.001<.00138
BLOOD_LymphomaMultivesicular body organization →+0.073+0.692<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,204 associations by consensus.

Exploration