Across TCGA cell cohorts, PPP1CC RNA expression is significantly associated with the go_rna of many other GO terms, with 4,742 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PPP1CC-associated GO terms across cancer lineages are Protein localization to kinetochore, Defense response to bacterium, and Regulation of G2/M transition of mitotic cell cycle. Each is linked with PPP1CC in more than 16 cancer types. Because this analysis shows association rather than direction, both PPP1CC-to-partner and partner-to-PPP1CC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1CC→partner) and Y-score (partner→PPP1CC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to kinetochore →	+0.184	+0.496	<.001	.003	3	17
UPPER_AERODIGESTIVE_TRACT	Defense response to bacterium →	-0.136	-0.804	<.001	<.001	3	16
OESOPHAGUS	Regulation of G2/M transition of mitotic cell cycle →	+0.097	+0.552	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Nuclear pore complex assembly →	+0.174	+0.951	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Nuclear pore organization →	+0.168	+1.034	<.001	<.001	3	16
OESOPHAGUS	Sister chromatid cohesion →	+0.152	+0.658	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,742 associations by consensus.

Exploration

PPP1CC survival (RNA) · tumor vs normal (RNA) · all PPP1CC data types