Across TCGA patient cohorts, PPP1CB protein abundance is significantly associated with the RNA expression of many other genes, with 9,902 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP1CB-associated genes across cancer lineages are DSTN, TCEAL4, and GSTM5. Each is linked with PPP1CB in more than 4 cancer types. Because this analysis shows association rather than direction, both PPP1CB-to-partner and partner-to-PPP1CB results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1CB→partner) and Y-score (partner→PPP1CB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DSTN →	+0.467	+0.240	.002	<.001	2	5
LSCC	TCEAL4 →	+0.419	+0.109	<.001	.003	3	4
UCEC	GSTM5 →	+0.863	+0.230	.001	<.001	3	4
UCEC	LPP →	+0.555	+0.170	.001	.008	3	4
LSCC	CFAP36 →	+0.385	+0.133	<.001	<.001	3	4
LSCC	CCDC121 →	+0.369	+0.102	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,902 associations by consensus.

Exploration

PPP1CB survival (RNA) · tumor vs normal (RNA) · all PPP1CB data types