PPP1CA

Across TCGA patient cohorts, PPP1CA RNA expression is significantly associated with the protein abundance of many other proteins, with 10,310 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP1CA-associated proteins across cancer lineages are NCAPD2, RAD9A, and RRM2. Each is linked with PPP1CA in more than 4 cancer types. Because this analysis shows association rather than direction, both PPP1CA-to-partner and partner-to-PPP1CA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1CA versus NCAPD2 in LSCC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1CA→partner) and Y-score (partner→PPP1CA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NCAPD2 →	+0.545	+0.406	<.001	<.001	3	5
COAD	RAD9A →	+0.449	+0.485	.003	.002	3	5
UCEC	RRM2 →	+0.710	+0.709	<.001	.002	3	5
UCEC	KIF4A →	+0.583	+0.635	.001	.007	3	5
BRCA	KDM2A →	+0.389	+0.603	<.001	<.001	3	5
LSCC	CDK1 →	+0.657	+0.341	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,310 associations by consensus.

PPP1CA vs NCAPD2 — LSCC

Explore this scatter interactively →