PPP1CA

Across TCGA patient cohorts, PPP1CA protein abundance is significantly associated with the protein abundance of many other proteins, with 16,032 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP1CA-associated proteins across cancer lineages are AIP, NFKB2, and PPP1R18. Each is linked with PPP1CA in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP1CA-to-partner and partner-to-PPP1CA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1CA versus AIP in UCEC, with a Pearson correlation of 0.52.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1CA→partner) and Y-score (partner→PPP1CA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AIP →	+0.310	+0.331	<.001	<.001	3	8
UCEC	NFKB2 →	+0.333	+0.209	<.001	<.001	3	7
LSCC	PPP1R18 →	+0.349	+0.199	<.001	<.001	3	6
COAD	PARP14 →	+0.360	+0.181	.002	.001	2	7
HNSC	RELA →	+0.176	+0.275	<.001	<.001	3	5
LSCC	STAT1 →	+0.586	+0.204	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,032 associations by consensus.

PPP1CA vs AIP — UCEC

Explore this scatter interactively →