PPOX

Across TCGA patient cohorts, PPOX RNA expression is significantly associated with the protein abundance of many other proteins, with 13,309 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPOX-associated proteins across cancer lineages are GATAD2B, PRCC, and CHAMP1. Each is linked with PPOX in more than 7 cancer types. Because this analysis shows association rather than direction, both PPOX-to-partner and partner-to-PPOX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPOX versus GATAD2B in GBM, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPOX→partner) and Y-score (partner→PPOX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GATAD2B →	+0.376	+0.388	<.001	<.001	3	8
BRCA	PRCC →	+0.373	+0.795	<.001	<.001	3	7
GBM	CHAMP1 →	+0.359	+0.335	<.001	<.001	3	7
HNSC	RPRD2 →	+0.318	+0.581	<.001	<.001	3	7
OV	POGZ →	+0.349	+0.489	<.001	.005	3	6
GBM	SMC1A →	+0.410	+0.338	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,309 associations by consensus.

PPOX vs GATAD2B — GBM

Explore this scatter interactively →