Across TCGA patient cohorts, PPM1N RNA expression is significantly associated with the RNA expression of many other genes, with 15,602 significant associations in total. UVM shows the largest number of these associations.

The most reproducible PPM1N-associated genes across cancer lineages are RTN2, GIPR, and FCHO1. Each is linked with PPM1N in more than 27 cancer types. Because this analysis shows association rather than direction, both PPM1N-to-partner and partner-to-PPM1N results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1N→partner) and Y-score (partner→PPM1N) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	RTN2 →	+1.374	+0.912	<.001	<.001	3	28
CHOL	GIPR →	+1.421	+1.097	.003	.005	2	25
UCEC	FCHO1 →	+1.201	+0.763	<.001	<.001	3	24
PAAD	VASP →	+0.731	+0.811	<.001	<.001	3	23
KIRP	IRF3 →	+0.665	+0.393	<.001	<.001	3	22
ACC	RRAS →	+1.103	+0.934	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,602 associations by consensus.

Exploration

PPM1N survival (RNA) · tumor vs normal (RNA) · all PPM1N data types