Across TCGA cell cohorts, PPM1N RNA expression is significantly associated with the go_rna of many other GO terms, with 2,371 significant associations in total. CNS shows the largest number of these associations.

The most reproducible PPM1N-associated GO terms across cancer lineages are Adult locomotory behavior, Negative regulation of cholesterol efflux, and Neuron-neuron synaptic transmission. Each is linked with PPM1N in more than 7 cancer types. Because this analysis shows association rather than direction, both PPM1N-to-partner and partner-to-PPM1N results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1N→partner) and Y-score (partner→PPM1N) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Adult locomotory behavior →	+0.170	+1.696	.006	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cholesterol efflux →	+0.197	+0.862	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Neuron-neuron synaptic transmission →	-0.148	-0.580	.001	.003	3	6
CNS	Amelogenesis →	-0.190	-0.810	.001	.002	3	6
LUNG_NSCLC_LUAD	Regulation of calcium ion-dependent exocytosis →	+0.057	+0.716	.001	.001	3	5
UPPER_AERODIGESTIVE_TRACT	Response to flavonoid →	+0.201	+0.764	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,371 associations by consensus.

Exploration

PPM1N survival (RNA) · tumor vs normal (RNA) · all PPM1N data types