PPM1M

Across TCGA patient cohorts, PPM1M RNA expression is significantly associated with the RNA expression of many other genes, with 18,164 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible PPM1M-associated genes across cancer lineages are RHOA, TNFSF12, and TWF2. Each is linked with PPM1M in more than 32 cancer types. Because this analysis shows association rather than direction, both PPM1M-to-partner and partner-to-PPM1M results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPM1M versus RHOA in KICH, with a Pearson correlation of 0.49.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1M→partner) and Y-score (partner→PPM1M) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KICH	RHOA →	+0.999	+0.951	<.001	<.001	2	33
LAML	TNFSF12 →	+1.652	+1.113	<.001	<.001	3	31
LIHC	TWF2 →	+0.886	+0.828	<.001	<.001	3	31
CHOL	GNAI2 →	+1.014	+1.087	<.001	.001	2	32
LAML	FGD2 →	+2.409	+1.219	<.001	<.001	3	31
THYM	TRAF3IP3 →	+1.484	+0.584	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,164 associations by consensus.

PPM1M vs RHOA — KICH

Explore this scatter interactively →