PPM1M

Across TCGA cell cohorts, PPM1M RNA expression is significantly associated with the RNA expression of many other genes, with 8,795 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPM1M-associated genes across cancer lineages are MST1, NPRL2, and GLT8D1. Each is linked with PPM1M in more than 9 cancer types. Because this analysis shows association rather than direction, both PPM1M-to-partner and partner-to-PPM1M results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPM1M versus MST1 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.57.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1M→partner) and Y-score (partner→PPM1M) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	MST1 →	+1.488	+0.769	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	NPRL2 →	+0.709	+0.749	<.001	<.001	3	9
LUNG_NSCLC_LUSC	GLT8D1 →	+0.795	+1.015	.002	.003	2	10
URINARY_TRACT	DALRD3 →	+0.931	+1.888	.001	<.001	3	9
URINARY_TRACT	DLG4 →	+2.024	+1.214	<.001	<.001	3	9
LIVER	TWF2 →	+1.056	+1.119	.008	.004	1	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,795 associations by consensus.

PPM1M vs MST1 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →