PPM1K

Across TCGA cell cohorts, PPM1K RNA expression is significantly associated with the go_rna of many other GO terms, with 5,132 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPM1K-associated GO terms across cancer lineages are Macroautophagy, Autophagosome organization, and Regulation of type 2 mitophagy. Each is linked with PPM1K in more than 12 cancer types. Because this analysis shows association rather than direction, both PPM1K-to-partner and partner-to-PPM1K results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by PPM1K-low versus PPM1K-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1K→partner) and Y-score (partner→PPM1K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Macroautophagy →	+0.078	+1.054	.004	.004	3	13
STOMACH	Autophagosome organization →	+0.053	+1.378	<.001	<.001	3	13
PANCREAS	Regulation of type 2 mitophagy →	+0.110	+0.812	.002	.003	3	11
STOMACH	COPII-coated vesicle cargo loading →	+0.111	+1.965	.003	<.001	3	11
STOMACH	Autophagy →	+0.056	+0.987	<.001	.005	3	11
BONE	Golgi vesicle transport →	+0.063	+1.185	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,132 associations by consensus.

Macroautophagy by PPM1K expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →