PPM1J

Across TCGA patient cohorts, PPM1J protein abundance is significantly associated with the RNA expression of many other genes, with 4,534 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPM1J-associated genes across cancer lineages are DPP4, TEF, and ABCG2. Each is linked with PPM1J in more than 2 cancer types. Because this analysis shows association rather than direction, both PPM1J-to-partner and partner-to-PPM1J results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPM1J versus DPP4 in UCEC, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1J→partner) and Y-score (partner→PPM1J) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DPP4 →	+2.406	+1.239	<.001	<.001	3	3
GBM	TEF →	+0.839	+0.496	<.001	<.001	3	3
UCEC	ABCG2 →	+1.555	+1.001	.007	.004	3	2
UCEC	RGS22 →	+2.007	+1.075	<.001	<.001	3	2
UCEC	KLRC1 →	+1.244	+1.025	<.001	<.001	3	2
UCEC	SAMD3 →	+0.931	+1.205	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,534 associations by consensus.

PPM1J vs DPP4 — UCEC

Explore this scatter interactively →