PPM1G

Across TCGA patient cohorts, PPM1G RNA expression is significantly associated with the protein abundance of many other proteins, with 21,039 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPM1G-associated proteins across cancer lineages are MCM2, MCM4, and UTP4. Each is linked with PPM1G in more than 8 cancer types. Because this analysis shows association rather than direction, both PPM1G-to-partner and partner-to-PPM1G results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPM1G versus MCM2 in LUAD, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1G→partner) and Y-score (partner→PPM1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MCM2 →	+0.742	+0.493	<.001	<.001	3	9
LUAD	MCM4 →	+0.780	+0.482	<.001	<.001	3	9
LSCC	UTP4 →	+0.493	+0.687	<.001	<.001	3	8
LUAD	MCM2_S139 →	+0.919	+0.451	<.001	<.001	3	8
LUAD	MCM6 →	+0.768	+0.482	<.001	<.001	3	8
GBM	CHAF1B →	+0.586	+0.248	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,039 associations by consensus.

PPM1G vs MCM2 — LUAD

Explore this scatter interactively →