PPM1G

Across TCGA cell cohorts, PPM1G RNA expression is significantly associated with the go_rna of many other GO terms, with 4,042 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PPM1G-associated GO terms across cancer lineages are Mitotic spindle elongation, rRNA transcription, and Mitotic spindle midzone assembly. Each is linked with PPM1G in more than 15 cancer types. Because this analysis shows association rather than direction, both PPM1G-to-partner and partner-to-PPM1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle elongation grouped by PPM1G-low versus PPM1G-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1G→partner) and Y-score (partner→PPM1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Mitotic spindle elongation →	+0.210	+1.040	<.001	<.001	3	16
BONE	rRNA transcription →	+0.125	+0.663	<.001	<.001	3	16
BLOOD_Lymphoma	Mitotic spindle midzone assembly →	+0.210	+1.040	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.201	+1.152	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA replication →	+0.201	+0.844	<.001	.002	3	15
SOFT_TISSUE	Meiotic chromosome condensation →	+0.176	+0.813	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,042 associations by consensus.

Mitotic spindle elongation by PPM1G expression — BLOOD_Lymphoma

Explore this box plot interactively →