PPM1A

Across TCGA cell cohorts, PPM1A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,908 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPM1A-associated GO terms across cancer lineages are Protein myristoylation, N-terminal protein amino acid modification, and Regulation of proteasomal ubiquitin-dependent protein catabolic process. Each is linked with PPM1A in more than 15 cancer types. Because this analysis shows association rather than direction, both PPM1A-to-partner and partner-to-PPM1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein myristoylation grouped by PPM1A-low versus PPM1A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1A→partner) and Y-score (partner→PPM1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein myristoylation →	+0.134	+0.600	<.001	<.001	3	16
BONE	N-terminal protein amino acid modification →	+0.166	+0.781	.001	.003	3	16
OVARY	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.052	+0.647	<.001	.001	3	13
OVARY	Autophagosome organization →	+0.075	+0.885	<.001	<.001	3	12
STOMACH	miRNA processing →	+0.107	+0.719	<.001	<.001	3	12
OVARY	Endosome to lysosome transport →	+0.051	+0.767	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,908 associations by consensus.

Protein myristoylation by PPM1A expression — BONE

Explore this box plot interactively →