PPL

Across TCGA patient cohorts, PPL RNA expression is significantly associated with the protein abundance of many other proteins, with 13,354 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPL-associated proteins across cancer lineages are PPL_S1657, PPL_S887, and PPL_S14. Each is linked with PPL in more than 8 cancer types. Because this analysis shows association rather than direction, both PPL-to-partner and partner-to-PPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPL versus PPL_S1657 in GBM, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPL→partner) and Y-score (partner→PPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPL_S1657 →	+0.847	+1.189	.003	.009	3	9
GBM	PPL_S887 →	+1.199	+2.028	.009	.001	2	9
GBM	PPL_S14 →	+1.551	+1.154	<.001	<.001	3	7
HNSC	EVPL →	+0.755	+1.051	<.001	<.001	3	7
BRCA	EVPL_S2025 →	+0.908	+0.834	.003	.006	3	7
LSCC	PPL_S830 →	+1.122	+1.163	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,354 associations by consensus.

PPL vs PPL_S1657 — GBM

Explore this scatter interactively →