PPIP5K2

Across TCGA patient cohorts, PPIP5K2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,767 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPIP5K2-associated proteins across cancer lineages are RPS6, RPL14, and RPL26. Each is linked with PPIP5K2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PPIP5K2-to-partner and partner-to-PPIP5K2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIP5K2 versus RPS6 in GBM, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIP5K2→partner) and Y-score (partner→PPIP5K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPS6 →	-0.534	-0.432	<.001	<.001	3	5
GBM	RPL14 →	-0.605	-0.453	<.001	<.001	3	4
GBM	RPL26 →	-0.692	-0.513	.008	.004	2	5
BRCA	RPL6 →	-0.538	-0.676	<.001	<.001	3	4
GBM	RPL7 →	-0.534	-0.418	<.001	<.001	3	4
UCEC	SEC63 →	-0.537	-0.351	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,767 associations by consensus.

PPIP5K2 vs RPS6 — GBM

Explore this scatter interactively →