PPIP5K2

Across TCGA patient cohorts, PPIP5K2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,256 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPIP5K2-associated genes across cancer lineages are DTWD2, AP3S1, and INPP5A. Each is linked with PPIP5K2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PPIP5K2-to-partner and partner-to-PPIP5K2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIP5K2 versus DTWD2 in COAD, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIP5K2→partner) and Y-score (partner→PPIP5K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DTWD2 →	+0.511	+0.223	.004	.003	3	5
COAD	AP3S1 →	+0.478	+0.247	.008	.001	3	5
HNSC	INPP5A →	-0.444	-0.128	.003	.003	3	5
OV	FBXO21 →	-0.746	-0.285	.001	<.001	3	4
OV	FEM1C →	+0.548	+0.257	<.001	<.001	3	4
BRCA	CSNK1G3 →	+0.449	+0.142	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,256 associations by consensus.

PPIP5K2 vs DTWD2 — COAD

Explore this scatter interactively →