PPIP5K2

Across TCGA patient cohorts, PPIP5K2 protein abundance is significantly associated with the protein abundance of many other proteins, with 18,826 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPIP5K2-associated proteins across cancer lineages are DMXL1, CERT1, and AP3D1. Each is linked with PPIP5K2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PPIP5K2-to-partner and partner-to-PPIP5K2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIP5K2 versus DMXL1 in BRCA, with a Pearson correlation of 0.40.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIP5K2→partner) and Y-score (partner→PPIP5K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DMXL1 →	+0.229	+0.198	<.001	<.001	3	8
GBM	CERT1 →	+0.257	+0.277	<.001	<.001	3	6
BRCA	AP3D1 →	+0.221	+0.163	<.001	<.001	3	6
COAD	AP3S1 →	+0.349	+0.311	<.001	<.001	3	6
LSCC	APOBR →	+0.501	+0.168	<.001	<.001	3	6
PDAC	RAC1 →	-0.722	-0.153	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,826 associations by consensus.

PPIP5K2 vs DMXL1 — BRCA

Explore this scatter interactively →