PPIP5K2

Across TCGA cell cohorts, PPIP5K2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,951 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PPIP5K2-associated GO terms across cancer lineages are Microtubule organizing center organization, Translesion synthesis, and Regulation of chromosome organization. Each is linked with PPIP5K2 in more than 13 cancer types. Because this analysis shows association rather than direction, both PPIP5K2-to-partner and partner-to-PPIP5K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule organizing center organization grouped by PPIP5K2-low versus PPIP5K2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIP5K2→partner) and Y-score (partner→PPIP5K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Microtubule organizing center organization →	+0.084	+0.911	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Translesion synthesis →	+0.082	+0.988	<.001	<.001	3	14
BLOOD_Myeloma	Regulation of chromosome organization →	+0.060	+0.524	<.001	.004	3	14
LUNG_NSCLC_LUSC	Error-prone translesion synthesis →	+0.110	+1.030	.004	.005	3	14
UPPER_AERODIGESTIVE_TRACT	Centrosome cycle →	+0.096	+0.980	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of microtubule-based process →	+0.056	+1.133	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,951 associations by consensus.

Microtubule organizing center organization by PPIP5K2 expression — LARGE_INTESTINE

Explore this box plot interactively →