PPIL4

Across TCGA patient cohorts, PPIL4 protein abundance is significantly associated with the RNA expression of many other genes, with 10,920 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPIL4-associated genes across cancer lineages are NUP43, PCMT1, and LTV1. Each is linked with PPIL4 in more than 6 cancer types. Because this analysis shows association rather than direction, both PPIL4-to-partner and partner-to-PPIL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIL4 versus NUP43 in HNSC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIL4→partner) and Y-score (partner→PPIL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NUP43 →	+0.807	+0.307	<.001	<.001	3	7
HNSC	PCMT1 →	+0.608	+0.256	<.001	<.001	3	7
HNSC	LTV1 →	+0.577	+0.163	.005	.001	3	7
HNSC	KATNA1 →	+0.646	+0.201	.003	<.001	3	7
OV	FAM120B →	+0.548	+0.249	<.001	<.001	3	6
HNSC	TBP →	+0.549	+0.214	.007	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,920 associations by consensus.

PPIL4 vs NUP43 — HNSC

Explore this scatter interactively →