PPIL2

Across TCGA patient cohorts, PPIL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,036 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPIL2-associated proteins across cancer lineages are FGA, ZNF318_S464, and ZMYM2. Each is linked with PPIL2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PPIL2-to-partner and partner-to-PPIL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIL2 versus FGA in GBM, with a Pearson correlation of -0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIL2→partner) and Y-score (partner→PPIL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FGA →	-0.426	-0.224	.001	.005	3	4
COAD	ZNF318_S464 →	+0.489	+0.400	.005	.009	3	4
LSCC	ZMYM2 →	+0.422	+0.454	<.001	<.001	3	4
BRCA	NFIA →	+0.414	+0.515	.006	.001	3	4
LSCC	NONO →	+0.169	+0.342	<.001	<.001	3	4
GBM	PLEC_T3634 →	-0.427	-0.277	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,036 associations by consensus.

PPIL2 vs FGA — GBM

Explore this scatter interactively →