PPIL1P1

Across TCGA pan-cancer cohorts, PPIL1P1 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated PPIL1P1 data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher PPIL1P1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PPIL1P1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and BLCA show a favorable association.

ESCA, ACC, and SKCM are the cancer types where PPIL1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	III,IV	0.557	0.331	.011	21	view →
ACC	DFS	Tertile	II,III,IV	0.242	0.724	.034	18	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	12	view →
KIRP	DFS	Tertile	All	0.764	0.933	.008	12	view →
BLCA	DFS	Tertile	All	0.829	0.558	.048	9	view →
SARC	OS	Tertile	All	0.553	0.783	.010	9	view →
PCPG	DFS	Tertile	All	0.566	0.876	.046	9	view →
LIHC	DFS	Tertile	All	0.338	0.564	.020	9	view →
LGG	DFS	Quartile	All	0.822	0.715	.023	7	view →
KIRC	DFS	Tertile	IV	0.645	0.351	.047	4	view →
STAD	OS	Median	III,IV	0.533	0.733	.030	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

PPIL1P1–ESCA (OS)

Open the ESCA breakdown →