PPIL1

Across TCGA patient cohorts, PPIL1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,317 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPIL1-associated genes across cancer lineages are POLR1H, OARD1, and SAYSD1. Each is linked with PPIL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PPIL1-to-partner and partner-to-PPIL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIL1 versus POLR1H in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIL1→partner) and Y-score (partner→PPIL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	POLR1H →	+0.655	+0.330	<.001	<.001	3	7
OV	OARD1 →	+0.624	+0.335	<.001	<.001	3	6
BRCA	SAYSD1 →	+0.551	+0.257	<.001	<.001	3	6
HNSC	UHRF1BP1 →	+0.627	+0.219	.006	.002	3	6
GBM	ZNF184 →	+0.573	+0.323	<.001	<.001	3	6
LSCC	GLO1 →	+0.788	+0.309	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,317 associations by consensus.

PPIL1 vs POLR1H — OV

Explore this scatter interactively →