PPIL1

Across TCGA patient cohorts, PPIL1 protein abundance is significantly associated with the protein abundance of many other proteins, with 14,718 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPIL1-associated proteins across cancer lineages are SRSF2, SRSF3, and TPR. Each is linked with PPIL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both PPIL1-to-partner and partner-to-PPIL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIL1 versus SRSF2 in COAD, with a Pearson correlation of 0.66.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIL1→partner) and Y-score (partner→PPIL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SRSF2 →	+0.261	+0.241	<.001	<.001	3	9
BRCA	SRSF3 →	+0.337	+0.269	<.001	<.001	3	8
BRCA	TPR →	+0.255	+0.234	<.001	<.001	3	8
BRCA	SNW1 →	+0.242	+0.221	<.001	<.001	3	8
GBM	RBM14 →	+0.265	+0.235	<.001	.001	2	9
OV	RTF1 →	+0.249	+0.318	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,718 associations by consensus.

PPIL1 vs SRSF2 — COAD

Explore this scatter interactively →