PPIL1

Across TCGA cell cohorts, PPIL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,839 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPIL1-associated GO terms across cancer lineages are Protein peptidyl-prolyl isomerization, Negative regulation of RNA export from nucleus, and DNA replication. Each is linked with PPIL1 in more than 19 cancer types. Because this analysis shows association rather than direction, both PPIL1-to-partner and partner-to-PPIL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein peptidyl-prolyl isomerization grouped by PPIL1-low versus PPIL1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIL1→partner) and Y-score (partner→PPIL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein peptidyl-prolyl isomerization →	+0.161	+1.048	<.001	<.001	3	20
BONE	Negative regulation of RNA export from nucleus →	+0.180	+0.852	<.001	.001	3	19
SOFT_TISSUE	DNA replication →	+0.118	+0.826	<.001	<.001	3	16
BONE	DNA-templated DNA replication →	+0.142	+0.713	<.001	.001	3	16
BONE	DNA replication initiation →	+0.186	+0.798	.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Maturation of SSU-rRNA →	+0.117	+0.824	.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,839 associations by consensus.

Protein peptidyl-prolyl isomerization by PPIL1 expression — PANCREAS

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