PPIAP84

Across TCGA pan-cancer cohorts, PPIAP84 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated PPIAP84 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher PPIAP84 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPIAP84 expression acts as an unfavorable survival marker, although some lineages such as BLCA and PRAD show a favorable association.

LIHC, KICH, and BLCA are the cancer types where PPIAP84 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	III,IV	0.224	0.425	.004	34	view →
KICH	DFS	Quartile	II,III,IV	0.197	0.907	<.001	18	view →
BLCA	OS	Tertile	III,IV	0.603	0.359	.011	18	view →
OV	DFS	Quartile	II,III,IV	0.331	0.407	.020	16	view →
STAD	OS	Tertile	All	0.419	0.636	.034	15	view →
ACC	OS	Tertile	II,III,IV	0.696	0.962	.008	15	view →
THYM	OS	Quartile	All	0.716	0.962	.014	12	view →
PRAD	OS	Median	All	0.983	0.753	.012	10	view →
GBM	OS	Median	All	0.221	0.306	.018	9	view →
PCPG	OS	Tertile	All	0.824	0.969	.017	9	view →
PAAD	OS	Quartile	All	0.274	0.545	.028	6	view →
LGG	DFS	Quartile	All	0.588	0.788	.001	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

PPIAP84–LIHC (OS)

Open the LIHC breakdown →