PPIAP80

Across TCGA pan-cancer cohorts, PPIAP80 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PPIAP80 data layer compared with 18 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PPIAP80 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PPIAP80 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

LUAD and SKCM are the cancer types where PPIAP80 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.410	0.813	<.001	23	view →
SKCM	DFS	Median	All	1.000	0.602	.029	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

PPIAP80–LUAD (OS)

Open the LUAD breakdown →