PPIAP77

Across TCGA pan-cancer cohorts, PPIAP77 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated PPIAP77 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher PPIAP77 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPIAP77 expression acts as an unfavorable survival marker, although some lineages such as LUSC and HNSC show a favorable association.

ACC, LUSC, and STAD are the cancer types where PPIAP77 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.772	0.964	<.001	83	view →
LUSC	DFS	Quartile	II,III,IV	0.556	0.300	.001	69	view →
STAD	OS	Quartile	II,III,IV	0.356	0.692	.003	48	view →
LGG	DFS	Median	All	0.650	0.824	<.001	48	view →
UVM	DFS	Quartile	III,IV	0.212	0.853	.004	42	view →
KICH	DFS	Tertile	II,III,IV	0.689	1.000	.006	37	view →
HNSC	DFS	Median	IV	0.595	0.298	.001	36	view →
COAD	DFS	Tertile	III,IV	0.511	0.308	.005	23	view →
READ	DFS	Median	All	0.902	0.535	.001	22	view →
THYM	DFS	Quartile	II,III,IV	0.736	0.949	.019	18	view →
KIRP	DFS	Tertile	III,IV	0.252	0.655	.004	18	view →
LIHC	OS	Quartile	All	0.615	0.811	.003	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

PPIAP77–ACC (OS)

Open the ACC breakdown →