PPIAP72

Across TCGA pan-cancer cohorts, PPIAP72 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated PPIAP72 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher PPIAP72 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPIAP72 expression acts as an unfavorable survival marker, although some lineages such as GBM and HNSC show a favorable association.

ACC, LUSC, and KIRC are the cancer types where PPIAP72 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	II,III,IV	0.322	0.929	<.001	90	view →
LUSC	DFS	Tertile	III,IV	0.185	1.000	<.001	34	view →
KIRC	OS	Tertile	All	0.550	0.708	.002	28	view →
LIHC	DFS	Tertile	All	0.479	0.625	.012	17	view →
CHOL	DFS	Tertile	II,III,IV	0.096	0.833	.004	16	view →
GBM	OS	Median	All	0.521	0.289	.004	15	view →
HNSC	OS	Median	II,III,IV	0.698	0.597	.007	15	view →
ESCA	DFS	Median	All	0.275	0.447	.010	14	view →
BRCA	DFS	Quartile	IV	0.396	0.892	.026	14	view →
UCS	DFS	Tertile	IV	0.975	0.296	.024	12	view →
UVM	DFS	Quartile	III,IV	0.174	0.564	.021	12	view →
LUAD	OS	Tertile	III,IV	0.536	0.166	.021	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

PPIAP72–ACC (OS)

Open the ACC breakdown →