peptidylprolyl isomerase A pseudogene 70Genealiases: []
Q-omics provides the consensus-scored PPIAP70 profile across patient tissues and cancer cell-line models. PPIAP70 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, PPIAP70 is differentially expressed in 4, with the highest sampling consensus in HNSC. Additionally, PPIAP70 RNA expression shows 7,834 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight UCEC, HNSC, and GBM as cancer lineages where PPIAP70 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PPIAP70 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PPIAP70 survival associations across molecular data types. PPIAP70 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PPIAP70 RNA expression–survival associations across cancer types. High PPIAP70 expression shows unfavorable associations in UCEC, ACC, KICH, LUAD and LIHC, but favorable associations in COAD. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for PPIAP70 RNA expression.
This table summarizes PPIAP70 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for PPIAP70. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PPIAP70 shows higher tumor expression in HNSC, UCEC, COAD and STAD. The HNSC box plot shows higher PPIAP70 RNA expression in tumor versus normal tissue (log2 FC = +0.089, t-test p = .003).
This table shows molecular features associated with PPIAP70 in patient tissues and cancer cell lines. In patient samples, PPIAP70 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
