PPIAP69

Q-omics provides the consensus-scored PPIAP69 profile across patient tissues and cancer cell-line models. PPIAP69 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in UVM. Additionally, PPIAP69 RNA expression shows 5,957 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight UVM, and STAD as cancer lineages where PPIAP69 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes PPIAP69 survival associations across molecular data types. PPIAP69 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

PPIAP69 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	8	UVM (81)	view →

This table ranks reproducible PPIAP69 RNA expression–survival associations across cancer types. High PPIAP69 expression shows unfavorable associations in UVM, UCEC, KIRP, BRCA and DLBC, but favorable associations in KIRC. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify UVM as the clearest survival context for PPIAP69 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	II,III,IV	0.213	0.718	.002	81	view →
UCEC	DFS	Tertile	III,IV	0.089	0.587	.006	72	view →
KIRP	OS	Tertile	All	0.218	0.724	<.001	54	view →
KIRC	DFS	Tertile	II,III,IV	1.000	0.679	.017	48	view →
BRCA	OS	Tertile	III,IV	0.124	0.548	.037	12	view →
DLBC	OS	Tertile	II,III,IV	0.118	0.802	.025	9	view →

Pink = unfavorable, green = favorable. all 8 lineages →

PPIAP69-UVM (OS)

Explore this curve interactively →