PPIAP67

Across TCGA pan-cancer cohorts, PPIAP67 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of PPIAP67’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where PPIAP67 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PPIAP67 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

HNSC, KICH, and UCEC are the cancer types where PPIAP67 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PPIAP67 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+0.220	.006	8	view →
KICH	Female	All	−0.353	<.001	7	view →
UCEC	All	All	−0.447	<.001	4	view →
KIRC	Male	II,III,IV	−0.180	.002	4	view →
CHOL	All	All	+0.362	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

PPIAP67–HNSC

Open the HNSC breakdown →