Q-omics provides the consensus-scored PPIAP63 profile across patient tissues and cancer cell-line models. PPIAP63 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in UCEC. Additionally, PPIAP63 RNA expression shows 3,888 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight UCEC, and ESCA as cancer lineages where PPIAP63 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes PPIAP63 survival associations across molecular data types. PPIAP63 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

PPIAP63 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	10	UCEC (90)	view →

This table ranks reproducible PPIAP63 RNA expression–survival associations across cancer types. High PPIAP63 expression shows unfavorable associations in UCEC, KIRC, COAD, ACC, HNSC and LIHC. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for PPIAP63 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.676	0.928	<.001	90	view →
KIRC	DFS	Tertile	IV	0.106	0.640	<.001	84	view →
COAD	OS	Tertile	II,III,IV	0.140	0.859	<.001	63	view →
ACC	OS	Tertile	All	0.273	0.802	.017	45	view →
HNSC	OS	Tertile	IV	0.059	0.708	<.001	36	view →
LIHC	DFS	Tertile	All	0.096	0.557	<.001	36	view →

Pink = unfavorable, green = favorable. all 10 lineages →

PPIAP63-UCEC (OS)

Kaplan–Meier survival curve for PPIAP63 RNA expression in UCEC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with PPIAP63 in patient tissues and cancer cell lines. In patient samples, PPIAP63 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	3,888	ESCA (1898)	view →
Function (RNA)	2,238	STAD (2123)	view →