PPIAP6

Across TCGA patient cohorts, PPIAP6 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,408 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPIAP6-associated proteins across cancer lineages are GMPPA, YY1, and IGHV3-35. Each is linked with PPIAP6 in more than 3 cancer types. Because this analysis shows association rather than direction, both PPIAP6-to-partner and partner-to-PPIAP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIAP6 versus GMPPA in LSCC, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP6→partner) and Y-score (partner→PPIAP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GMPPA →	-0.366	-0.644	<.001	.001	3	4
LSCC	YY1 →	+0.227	+0.541	<.001	.004	3	3
LSCC	IGHV3-35 →	-0.400	-0.438	<.001	.001	3	3
LSCC	MBD3 →	+0.404	+0.817	.001	<.001	3	3
OV	MGA_S924 →	+0.684	+1.177	.001	<.001	3	3
OV	RIN1_S333 →	-0.644	-0.825	.002	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,408 associations by consensus.

PPIAP6 vs GMPPA — LSCC

Explore this scatter interactively →