Across TCGA patient cohorts, PPIAP59 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,700 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAP59-associated GO terms across cancer lineages are Negative regulation of mitotic cell cycle, Negative regulation of mitotic cell cycle phase transition, and U2-type prespliceosome assembly. Each is linked with PPIAP59 in more than 7 cancer types. Because this analysis shows association rather than direction, both PPIAP59-to-partner and partner-to-PPIAP59 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP59→partner) and Y-score (partner→PPIAP59) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of mitotic cell cycle →	+0.036	+0.238	<.001	<.001	3	8
STAD	Negative regulation of mitotic cell cycle phase transition →	+0.038	+0.230	<.001	<.001	3	7
STAD	U2-type prespliceosome assembly →	+0.051	+0.232	<.001	<.001	3	7
STAD	Positive regulation of amide metabolic process →	+0.031	+0.148	<.001	<.001	3	7
STAD	Ribosome assembly →	+0.050	+0.254	<.001	<.001	3	7
STAD	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.046	+0.262	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,700 associations by consensus.

Exploration

PPIAP59 survival (RNA) · tumor vs normal (RNA) · all PPIAP59 data types