PPIAP55

Across TCGA pan-cancer cohorts, PPIAP55 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of PPIAP55’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PPIAP55 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PPIAP55 is over-expressed in tumor.

COAD, LIHC, and LUAD are the cancer types where PPIAP55 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PPIAP55 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.427	<.001	7	view →
LIHC	All	III,IV	+0.162	.002	6	view →
LUAD	All	All	+0.192	.007	4	view →
KIRC	All	All	+0.085	.007	4	view →
CHOL	All	All	+0.378	<.001	3	view →
BLCA	All	III,IV	+0.183	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

PPIAP55–COAD

Open the COAD breakdown →