PPIAP52

Across TCGA pan-cancer cohorts, PPIAP52 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PPIAP52 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher PPIAP52 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPIAP52 expression acts as an unfavorable survival marker, although some lineages such as ESCA and BRCA show a favorable association.

STAD, KIRC, and ESCA are the cancer types where PPIAP52 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	All	0.224	0.467	.002	75	view →
KIRC	DFS	Median	All	0.774	0.922	.003	56	view →
ESCA	DFS	Quartile	All	1.000	0.120	.001	37	view →
BRCA	OS	Quartile	III,IV	0.950	0.789	.002	30	view →
LUAD	DFS	Tertile	All	0.704	0.820	.003	28	view →
PCPG	DFS	Tertile	All	0.447	0.911	<.001	19	view →
ACC	DFS	Quartile	All	0.269	0.669	.006	18	view →
KICH	DFS	Tertile	All	0.592	0.954	.011	15	view →
MESO	OS	Median	All	0.203	0.344	.019	15	view →
READ	DFS	Quartile	III,IV	1.000	0.644	.015	11	view →
OV	OS	Tertile	IV	0.570	0.280	.004	10	view →
DLBC	DFS	Median	IV	1.000	0.281	.005	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

PPIAP52–STAD (OS)

Open the STAD breakdown →